Analysis of dental and facial changes and nasal function in adults

Not Applicable

• Conditions: Maxillary deficiency in adults; Oral Health

• Registration Number: ISRCTN77018128
• Lead Sponsor: niversity of Alberta

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-05-02
• Last Update Posted: 15 May 2023
• Study Completion: 2027-12-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

1. Requirement of maxillary expansion treatment for the groups
2. Need for post-expansion orthognathic surgery
3. Full permanent dentition erupted (except 3rd molars)
4. Treatment may involve post-expansion tooth extraction or not
5. No syndromic characteristics or systematic diseases clinically determined or based on previous records
6. Male and female aged 18-30 years

Exclusion Criteria

Patients with palates too narrow for placement of the expander appliance, with large tori and/or asymmetric (canted) maxillary palatal plane

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Skeletal and airway changes to measure expansion using cone-beam computed tomography (CBCT) images, dental scan, photos, airway measurements and questionnaires at baseline, 12 months, end of active treatment and end of retention at 2 years. Expansion is measured using CBCT images, and dental scans. Changes in nasal volume and shape obtained will be obtained from the CBCT images after applying the AVIZO software. Airway resistance and nasal peak airflow will be compared between groups and the association between airway resistance and nasal volume/shape is measured using CBCT and polysomnography.<br>

Secondary Outcome Measures

Name	Time	Method
Dental expansion changes measured using CBCT images, dental scans, photos, airway measures and questionnaires at baseline, 12 months, end of active treatment and end of retentions, questionnaires, etc.