Determinants of the onset and progression of diabetic retinopathy in south China: Guangzhou Diabetic Eye Study

Not Applicable

Active, not recruiting

• Conditions: Diabetic retinopathy screening among people with diabetes; Eye Diseases; Diabetic retinopathy

• Registration Number: ISRCTN15853192
• Lead Sponsor: Sun Yat-sen University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-04-13
• Last Update Posted: 2022-01-24
• Study Completion: 2025-10-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 1185

Inclusion Criteria

1. Aged 35–85 years
2. Diagnosed type 2 diabetes confirmed by medical records from endocrinologists, insulin treatments, oral medicine, fasting blood glucose =7.0 mmol/L for at least two consecutive measurements or postprandial blood glucose =11.1 mmol/L
3. Ocular-treatment-naïve eyes

Exclusion Criteria

1. Any severe systemic disease, such as ischemic heart disease, stroke, cancer and kidney disease, or a history of systemic surgery, such as cardiac bypass, thrombolysis and kidney transplantation
2. Any cognitive disorder, mental disorder or failure to finish the questionnaire and all the examinations
3. Combined glaucoma, age-related macular degeneration, glaucoma, vitreous macular disease (vitreous haemorrhage, retinal detachment), amblyopia and other eye diseases
4. A history of intraocular surgery, such as retinal laser, intraocular anti-VEGF injection, glaucoma surgery, cataract surgery, laser myopia surgery and vitreoretinal surgery history
5. A failure of mydriasis due to corneal ulcer, severe refractive media turbidity or shallow anterior chamber and angle closure glaucoma

Study & Design

• Study Type: Observational
• Study Design: Not specified