Automatic Ventilation in Prehospital Resuscitation on OHCA
- Conditions
- Out-Of-Hospital Cardiac Arrest
- Interventions
- Device: Manual ventilationDevice: Automatic ventilation
- Registration Number
- NCT06067204
- Lead Sponsor
- National Taiwan University Hospital
- Brief Summary
The goal of this randomized controlled trial is to compare prehospital ventilation strategies in out-of-hospital cardiac arrest. The intervention group is automatic ventilation and the control group is manual ventilation. The main questions it aims to answer are:
1. How does automatic ventilation affect OHCA patients' survival and prognosis comparing to manual ventilation.
2. What are the differences on resuscitation qualities between automatic ventilation and manual ventilation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 514
- Age over 18 years old at the time of occurrence of out-of-hospital cardiac arrest (OHCA).
- Attended by the Hsinchu County Fire Department for emergency medical assistance.
- Pregnant women.
- OHCA caused by trauma.
- Return of spontaneous circulation (ROSC) observed at the scene.
- Clearly deceased at the scene (reaching conditions such as decomposition, rigor mortis, severe burns, decapitation, evisceration, or trunk fracture).
- Refusal of medical transportation by family members.
- No placement of an advanced airway throughout the procedure.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Manual ventilation Manual ventilation After the advanced airway is placed, a bag valve mask resuscitator will be connected and provides ventilation in every 6 seconds by the emergency medical technician. Automatic ventilation Automatic ventilation After the advanced airway is placed, an automatic pneumatic ventilator will be connected and provides ventilation in every 6 seconds.
- Primary Outcome Measures
Name Time Method The percentage of any return of spontaneous circulation (ROSC) 2 hours The patient achieved ROSC in prehospital or inhospital resuscitation.
- Secondary Outcome Measures
Name Time Method The percentage of sustained ROSC in 24 hours up to 24 hours The patient survives for 24 hours after arriving the hospital.
The percentage of epinephrine injection up to 1 hour Whether the patient has epinephrine injected in the prehospital setting.
The satisfaction of emergency medical technician (EMT) during the dispatch up to 5 hours The outcome contained five questions:
* More convenient to use
* Shorter time required to complete ventilation (from advanced airway placement to the start of ventilation)
* Smoother patient transport process
* Ability to perform more emergency medical techniques
* Overall satisfaction with the execution of emergency medical tasks
The EMTs answer in the 5-level scale (highly disagree, disagree, neutral, agree, highly agree)The percentage of intravenous catheter placement up to 1 hour Whether the patient has an IV catheter placed in the prehospital setting.
The percentage of survival to hospital discharge up to 90 days The patient survives to discharge from the hospital.
The percentage of favorable neurological outcome after discharge up to 90 days The patient survives to discharge from the hospital with Cerebral Performance Categories Scale 1 or 2.
Chest compression fraction up to 1 hour The chest compression fraction during prehospital resuscitation recorded by the monitor.
The percentage of pneumothorax up to 3 days Unilateral, bilateral or tension pneumothorax which might be associated with the ventilation strategy.
Trial Locations
- Locations (1)
National Taiwan University Hospital Hsinchu Branch
🇨🇳Hsinchu, Taiwan