The Prognostic Assessment of Extubation in Aged Patients With Multiple Organ Dysfunction Syndrome

• Conditions: Multiple Organ Dysfunction Syndrome

• Registration Number: NCT01802983
• Lead Sponsor: Chinese PLA General Hospital

Brief Summary

The multiple organ dysfunction syndrome (MODS) has remained the major factor contributing to prolongation of intensive and mortality. It is reported that the mortality rates have varied between 20% and 100%, depending on number, severity, duration, type and combination, and definition of dysfunction. In our study, the investigators explore some comprehensive treatment technology to improved outcomes of MODS patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-01
• Status Verified: 2013-02
• Study First Submitted: 2013-02-27
• Study First Submitted QC: 2013-03-01
• Last Update Submitted: 2013-03-01
• Study First Posted: 2013-03-04
• Last Update Posted: 2013-03-04
• Primary Completion: 2013-12
• Study Completion: 2013-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

• age > 60 years old;
• presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention;
• have trachea intubation after admitting to intensive care unit within 24 hours.

Exclusion Criteria

• end stage multiple organ failure.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the prognostic assessment of aged patients with MODS	28 days	According to the outcomes of 28-day,all the enrolled patients were divided into survival group and death group, clinical datum of which were collected and analysed. And then these prognosis were evaluated with the current scoring systems \[(Acute Physiology and Chronic Health EvaluationⅡ(APACHEⅡ, APACHE Ⅲ), Sample Acute Physiological score(SAPSⅡ), Multiple Organ Dysfunction score(MODS)\], the predictive power of which were compared by receiver operating characteristic(ROC) curve. Finally, a binary logistic regression analysis was performed to evaluate the concerning prognostic factors of MODSE.

Trial Locations

Locations (1)

Chinese PLA General Hospital; 🇨🇳 Beijing, Beijing, China