The effects of coconut and fish oil on postprandial triglycerides (COmega Trial).

Not Applicable

Completed

• Conditions: Postprandial blood lipids; Metabolic and Endocrine - Normal metabolism and endocrine development and function; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12619000921189
• Lead Sponsor: niversity of Newcastle

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-07-02
• Study Completion: 2019-07-26
• Last Update Posted: 9 November 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

•Healthy male or female
•Aged between 18 and 70 years

Exclusion Criteria

•BMI > 40 kg/m2
•Pregnant or breast feeding
•Taking hypolipidaemic medications (e.g. Lipitor, Crestor, Zocor)
•Taking regular dietary supplements known to influence blood lipid levels (e.g. fish oil, fibre, curcumin)
•Dieting or have any eating disorders
•Strong allergies/intolerances/sensitivities to any of the food products or ingredients used in the study
•History of congestive heart failure, stroke, myocardial infarction, coronary artery bypass graft, or atherosclerotic CVD; or pulmonary disease
•A chronic inflammatory disease (e.g. cancer)
•Diabetes Mellitus (Type 1 and Type 2)
•Liver or kidney related diseases
•Fasting triglyceride levels higher than 3.0 mmol/L
•History of gastrointestinal disorder and gall bladder disease
•Smoke
•History of severe neurological diseases or seizures
•Pace maker implants
•Vegetarian or vegan
•Exercise more than 30minutes/d on four or more days of the week

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood triglyceride concentration[Week 1, week 2, week 3 and week 4. <br>At each visit, this outcome will be measured at timepoints: 0 hours (before ingestion of food) and 2 hours, 3 hours, 3.5 hours, 4 hours, 4.5 hours and 5 hours post meal consumption.]

Secondary Outcome Measures

Name	Time	Method
Composite secondary outcome: blood cholesterol concentrations (total cholesterol, LDL-cholesterol, HDL-cholesterol, total cholesterol-to-HDL cholesterol ratio)[Week 1, Week 2, Week 3 and Week 4. At each visit, this outcome will be measured at timepoints: 0 hours (before ingestion of food) and 2 hours, 3 hours, 3.5 hours, 4 hours, 4.5 hours and 5 hours post meal consumption.];Postprandial blood glucose concentration[Week 1, week 2, week 3 and week 4. At each visit, this outcome will be measured at timepoints: 0 hours (before ingestion of food) and 2 hours post meal consumption.]