To compare the efficacy of topical 0.1% Betamethasone valerate and fractional co2 laser with topical 0.1% Betamethasone valerate in treatment of Alopecia areata

Not yet recruiting

• Conditions: Alopecia areata, unspecified,

• Registration Number: CTRI/2023/07/055395
• Lead Sponsor: Dr KVignesh kumar

Brief Summary

Alopecia areata is a complex genetic immune mediated inflammatory non scarring hair loss that results in decrease in quality of life. It may affect any hairy area in body and is usually reversible. Alopecia areata postulated to be hair specific autoimmune disease, with genetic factors playing role in disease susceptibility and severity. In acute progressive stage of alopecia areata , lymphocytic infiltration are seen around and sometimes with in the hair bulb region of anagen follicles

Despite the presence of this inflammatory infiltrate, the follicle retains its potential to produce hair, implying that the follicular stem cells remain viable. The chronic relapsing nature of alopecia areata and its profound effect on physical appearance make the development this condition distressing and life changing event for many affected individuals

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-08
• Last Update Posted: 2023-07-18

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patient with alopecia areata patients will be divided into Group A & Group B.
• Each group comprising of 40 patients.
• 40 patients in Group A will be use topical 0.1% betamethasone alone 40 patients in Group B will treated with fractional co2 with topical 0.1% betamethasone.
• Maximum 6 sittings will be given at 2 weeks interval.

Exclusion Criteria

• Before starting the study Pregnant and lactating women.
• Women planning for pregnancy Children less than 14 years During Study If patient wants alternate treatment during the study.
• If patient wants to discontinue the treatment.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hair regrowth in alopecia patches	24 weeks post study

Secondary Outcome Measures

Name	Time	Method
atrophy of skin	12 weeks post study

Trial Locations

Locations (1)

Chengalpattu Medical College, Chengalpattu.; 🇮🇳 Kancheepuram, TAMIL NADU, India

Chengalpattu Medical College, Chengalpattu.

🇮🇳Kancheepuram, TAMIL NADU, India

KVignesh kumar

Principal investigator

07418561171

vigneshkumarsmc@gmail.com