Comparative evaluation of the efficacy of LASER, desensitizing agent, and their combined effects on dentinal hypersensitivity– An In Vivo Study
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Reduction in the symptoms of dentinal hypersensitivity with each treatment protocol over a defined follow-up period.
研究概览
简要总结
Dentin hypersensitivity (DHS) represents as a pain of short and sharp nature but of rapid onset, this arises from exposed dentin in response to osmotic, thermal, chemical, or mechanical stimuli which cannot be attributed to any other form of dental disease or defect. The Hydrodynamic theory given by Brännström in 1964 is the most accepted theory. It states that an immediate pain response occurs when any stimuli cause rapid displacement of dentinal fluid within the tubules resulting in excitation of intradental nerves. Based on this theory, successful treatment of DHS depends on preventing or reducing fluid flow within the tubules. Thus, using different means to seal the open orifices of the dentinal tubule is the chief requirement. The present study will aim to compare and assess the decrease in symptoms of dentinal hypersensitivity using desensitizing agent, Diode laser and in combination.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with no systemic diseases were recruited.
- •Patients with a sensitivity score of 2 or more to the air blast stimulus as recorded on verbal analog scale.
排除标准
- •Carious teeth, restored teeth, and patients undergoing desensitizing therapy.
- •Allergic to ingredients used in the study.
- •Chronic users of anti-inflammatory and analgesic drugs.
- •Fractured or cracked teeth.
结局指标
主要结局
Reduction in the symptoms of dentinal hypersensitivity with each treatment protocol over a defined follow-up period.
时间窗: Baseline(Day1), Day7, Day14
次要结局
- 1. Reduction in the Verbal Analog Score of with each treatment protocol over a defined follow-up period.(2. Potential synergistic effects of combined treatment protocols compared to single treatments.)