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Antibiotics in Patients With Acute Respiratory Tract Infection With Procalcitonin as Parameter

Phase 2
Completed
Conditions
Respiratory Tract Infection
Registration Number
NCT00688610
Lead Sponsor
Hannover Medical School
Brief Summary

Antibiotics in patients with acute respiratory tract infections in primary care in consideration of procalcitonin as additive parameter.

The purpose of this study is to compare the ordinary manner of antibiotic- prescription with the prescription in consideration of procalcitonin-value in patients with acute respiratory tract infections.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
571
Inclusion Criteria
  • 18 years or older
  • Informed consent
  • Respiratory tract infection based on the clinical judgement of the primary care physician
Exclusion Criteria
  • Antibiotic pretreatment in previous 14 days
  • Portal hypertension
  • Major surgeries or multiple trauma which require hospitalization, in previous 4 weeks
  • Autoimmune disease and systemic diseases (lupus erythematodes, wegener´s disease)
  • Peritoneal dialysis
  • Acute treated or recently operated medullary c-cell-carcinoma, SCLC, carcinoid
  • Other inflammatory diseases (e.g. urinary tract infection, pyelonephritis, pancreatitis

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
days with significant impairment due to acute respiratory tract infection14 to 28 days after infection
Secondary Outcome Measures
NameTimeMethod
number of antibiotic prescriptions28 days

Trial Locations

Locations (1)

Medical School Hannover, Department Pneumology

🇩🇪

Hannover, Germany

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