NCT06438523招募中不适用
A-prf,Nanochitosan Combined With A-prf Scaffold Compared to Chitosan in Vital Pulp Therapy for Symptomatic Irreversible Pulpitis of Mature Permanent Mandibular First Molar Teeth .Randomized Controlled Trials
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- pain assessment
研究概览
简要总结
Clinical and radiographic assessment of A-prf,A-prf combined with nanochitosan compared to chitosan for symptomatic irreversible pulpits in lower permanent first molar
详细描述
3 groups are allocated using : Aprf Aprf combined with nanochitosan Chitosan
Each group will be subjected to tests:
Tooth sensibility via EPT (electrical pulp tester)and thermal test Radiolucency in digital radiograph Pain in NRS(6-12-24-72h)for 1 week
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 30 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients suffering from Symptomatic irreversible pulpitis in mature mandibular molars only will be involved.
- •Patients of either gender aged from 15-
- •Tooth should give positive response to cold test.
- •Haemostasias should be achieved after total pulpotomy.
- •The tooth is restorable and free from advanced periodontal disease, cracks and splits.
- •Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
- •Patients who will agree to the consent and will commit to follow-up period.
- •Patients with mature root.
- •Patients with no internal or external resorption and no periapical lesions.
- •Soft tissues around the tooth are normal with no swelling or sinus tract.
排除标准
- •Patients with immature roots.
- •Haemostasias after 10 minutes can not be controlled after total pulpotomy
- •Patients with any systemic disease that may affect normal healing.
- •Patients with periapical lesions or infections.
- •Pregnant females.
- •Patients who could/would not participate in a 6 months follow-up.
- •Patients with fistula or swelling
- •Patients with necrotic pulp.
- •Patients with old age.
结局指标
主要结局
pain assessment
时间窗: 6,12,24,72hours and 7 days postoperative
Pain assessment using numerical rate scale
次要结局
- Clinical and radiographic success(1,3,6,9and 12 months)
研究者
Mai Sherif
Researcher
Future University in Egypt
研究点 (2)
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