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Ex Vivo Evaluation of the Interest of the Association of Platinum With a Molecule BH3-mimetic ABT-737 in Samples of Ovarian Tumors

Completed
Conditions
Ovarian Cancer
Registration Number
NCT01440504
Lead Sponsor
Centre Francois Baclesse
Brief Summary

The aim of the study is to quantify the ex vivo induction of apoptosis by ABT-737 + association platinum in samples exposed and demonstrate the value of this combination compared to the agents used alone.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
36
Inclusion Criteria
  • Patient aged over 18 years
  • Ovarian cancer patients with at least five tumor samples does not affect the diagnosis, based on other tumor masses
  • Surgery of any initial chemotherapy naive
  • Patient information and signed informed consent
Exclusion Criteria
  • A person deprived of liberty or under guardianship
  • Insufficient tumor samples of ovarian cancer.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
rate of apoptotic cells2 years
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Centre François Baclesse

🇫🇷

Caen, France

Centre François Baclesse
🇫🇷Caen, France
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