Ex Vivo Evaluation of the Interest of the Association of Platinum With a Molecule BH3-mimetic ABT-737 in Samples of Ovarian Tumors
Completed
- Conditions
- Ovarian Cancer
- Registration Number
- NCT01440504
- Lead Sponsor
- Centre Francois Baclesse
- Brief Summary
The aim of the study is to quantify the ex vivo induction of apoptosis by ABT-737 + association platinum in samples exposed and demonstrate the value of this combination compared to the agents used alone.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 36
Inclusion Criteria
- Patient aged over 18 years
- Ovarian cancer patients with at least five tumor samples does not affect the diagnosis, based on other tumor masses
- Surgery of any initial chemotherapy naive
- Patient information and signed informed consent
Exclusion Criteria
- A person deprived of liberty or under guardianship
- Insufficient tumor samples of ovarian cancer.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rate of apoptotic cells 2 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Centre François Baclesse
🇫🇷Caen, France
Centre François Baclesse🇫🇷Caen, France