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Clinical Trials/ISRCTN74336585
ISRCTN74336585
Completed
Not Applicable

Patient controlled analgesia (PCA) versus continuous infusion (CI) of morphine during vaso-occlusive crisis in sickle cell disease (SCD): a randomised controlled trial

Academic Medical Centre (AMC) (The Netherlands)0 sites25 target enrollmentApril 28, 2006
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ConditionsSickle cell diseaseHaematological DisordersSickle-cell disorders

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sickle cell disease
Sponsor
Academic Medical Centre (AMC) (The Netherlands)
Enrollment
25
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 28, 2006
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Academic Medical Centre (AMC) (The Netherlands)

Eligibility Criteria

Inclusion Criteria

  • •1\. Sickle cell disease defined as HbSS, HbSC or HbSA (by electrophoresis)
  • •2\. Age greater than 17 years
  • •3\. The presence of typical pain recognised by patients as originating from vaso\-occlusive crisis and which cannot be explained by other causes
  • •4\. Severe pain necessitating treatment with intravenous morphine
  • •5\. Written informed consent

Exclusion Criteria

  • •1\. Patients already receiving opioids for more than 24 hours at time of randomisation
  • •2\. Allergy or intolerance for morphine
  • •3\. Pregnancy
  • •4\. Chronic use of opioids

Outcomes

Primary Outcomes

Not specified

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