Prognostic Value of Assessing Hypoxia in Tumours Using 18FMISO PET During a Course of Radiation Therapy – Proof of Concept Study

Not Applicable

• Conditions: Hypoxia in cancer; Cancer - Cervical (cervix); Cancer - Lung - Non small cell

• Registration Number: ACTRN12613001379707
• Lead Sponsor: Royal Brisbane and Women's Hospital Research Advisory Committee

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-12-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Cervical Cancer:
FIGO 2008 stage IB1 & node positive, IB2, II, IIIB or IVA disease.
Histological diagnosis of squamous cell carcinoma, adenocarcinoma or adenosquamous cell carcinoma of the cervix

NSCLC:
IASLC stage 2B to 3B.
Subject must have cytologically or histologically confirmed NSCLC

All participants:
Age >/= 18 years of age
ECOG performance status 0-2
Adequate bloods and renal function

Exclusion Criteria

Any prior radiotherapy to the same area.
Previous chemotherapy for the cancer.
Evidence of distant metastases
Concurrent illness, including severe infection that may jeopardize the ability of the patient to undergo the procedures outlined in this protocol with reasonable safety
Serious medical or psychiatric conditions that might compromise management according to the protocol.
Inability to comply with all study requirements
Pregnancy, lactation, or inadequate contraception.

Study & Design

• Study Type: Interventional
• Study Design: Not specified