NL-OMON39456已完成不适用
Cyp3A4 metabolism before and after surgery induced weight loss in morbidly obese patients, using midazolam as a model drug - MEMO study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •- 20 Morbidly obese subjects scheduled for bariatric surgery. We will stratify subjects to 4 weight groups: 100-120 kg; 120-145 kg; 145-170 kg; >170 kg
- •- Age 18-60 year old
排除标准
- •- Prescription or use of either CYP3A4-activity inducing or decreasing medication.
- •- Use of product containing grapefruit, wild grape, banpeiyu, pomegranate, star fruit, and black berry within 2 weeks prior to a study visit
- •- Pregnancy, breastfeeding
- •- Renal insufficiency
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