EUCTR2017-004677-14-NL进行中（未招募）1 期
Dose IndividualizAtion of Beta-lactam and fluOroquinoLone AntiBiotics in ICU patients: to TDM or not to TDM and the effects on Outcome (DIABOLO-study) - DIABOLO
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- Erasmus MC
- 入组人数
- 250
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •All patients admitted to the ICU and given standard of care intravenous therapy of either one or both of the target antibiotic classes are included. Antibiotic initiation based on clinical suspicion of infection and/or cultured pathogens susceptible to the target drugs, initial dosage prescription, and duration of therapy are at the discretion of the attending physician.
- •In order to be eligible to participate in this study, a subject must also meet all of the following criteria:
- •=18 years of age
- •Receiving intravenous antibiotic therapy of the target drugs
- •Treatment should be aimed for at least 2 days.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 100
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 150
排除标准
- •A potential subject who meets any of the following criteria will be excluded from participation in this study:
- •Patient already enrolled in this trial
- •Antibiotic cessation before sampling
- •Medium care and burn wound patients admitted to the ICU
- •Patients receiving cefotaxime as prophylaxis only within the context of Selective Digestive tract Decontamination (SDD)
研究者
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