Comparison of successful abortion using misoprostol alone and misoprostol with vaginal estroge
Phase 3
- Conditions
- The first and second trimester abortions.Spontaneous abortion
- Registration Number
- IRCT20190208042655N2
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 120
Inclusion Criteria
Mother age more than 18 years
Gestational age up to 28 weeks
First gravidity
First cesarean section repeat
Body mass index between 25 to 35 kg/m2
Hemoglobin level more than 10 gr/d
Exclusion Criteria
Scar in the uterine
Leiomyoma in the uterine
Blood coagulation disorder
Previous attempts to induce abortion in the current pregnancy
A medical disorder that prohibits abortion for example heart failure
Allergy to misoprostol or estradiol
Cervicitis and vaginitis
Polyhydramnios
The patient withdrawal to participate in the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Successful abortion. Timepoint: Once, at the end of abortion. Method of measurement: Abortion product observation (placenta and fetus residual).
- Secondary Outcome Measures
Name Time Method umber of doses of misoprostol used. Timepoint: Once, at the end of abortion. Method of measurement: Counting misoprostol doses.;Need to surgery. Timepoint: Once, at the end of abortion. Method of measurement: Curettage or hysterectomy conducting.