Evaluating transcatheter arterial embolisation and an anti-inflammatory for improvement of foot pain in people with plantar fasciopathy – a pilot study

Barwon Health0 个研究点目标入组 40 人开始时间: 2019年12月12日最近更新: 2020年1月6日

适应症

试验速览

暂无简介。

•1.18 to 85 years of age
•2.Moderate to severe plantar heel pain
•3.Pain resistant to conservative treatment for at least 3 months
•a.at least one conventional therapy such as analgesia, NSAID, corticosteroid injection, orthotics, physiotherapy (e.g. stretching and/or strengthening exercises)
•4.Willing, able and mentally competent to provide informed consent
•a.able to read and understand the Patient Information and Consent Form which is written in English language

•1.Local infection
•2.Active malignancy
•3.Prior ipsilateral foot or ankle surgery
•4.Ipsilateral injection into the foot or ankle in the last 3 months
•5.Pregnant or trying to become pregnant during the study period
•6.History of allergy to contrast media
•7.History of allergy to carbapenem (eg, imipenem, ertapenem or meropenem), or having an immediate or severe hypersensitivity reaction to a penicillin or cephalosporin antibiotic;
•8.History of seizures or using valproate
•9.History of allergy to NSAIDs
•10.Reduced kidney function or failure (chronic or acute)
•a.Estimated GFR < 30ml/min.1.73m2
•b.People on dialysis
•11.Body weight greater than 200kg
•12.Platelets < 100 x 109/L
•13.INR > 1.5
•14.Moderate to severe pain in other lower limb joints
•15.Previous amputation of ipsilateral toe/s or other part of foot
•16.Current or previous ipsilateral foot ulcer
•17.Peripheral neuropathy lower limb/s
•18.Charcot neuroarthropathy
•19.Peripheral vascular disease
•20.Rheumatoid arthritis or seronegative arthropathies
•21.Ipsilateral foot or ankle pain (excluding plantar heel pain) due to conditions such as achilles tendinopathy or Hallux Abduco Valgus
•22.Severe hepatic impairment or heart failure
•23.Active or a history of gastrointestinal inflammatory disorder or ulceration, haemorrhage, chronic dyspepsia.
•24.History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy.
•25.Asthma with known sensitivity to NSAIDs

发起方