IRCT138904263325N3Completed未知
Effect of short-term and low amount of intravenous Ascorbic Acid on reducing ferritin in Hemodialysis Patients without increasing the start dosage of erythropoietin: crossed over double blind randomized controlled trial
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Enrollment
- 30
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- no limit to no limit (—)
- Sex
- All
Inclusion Criteria
- •receiving hemodialysis therapy for at least 6 months, administered EPO for 6 months or longer at a dose of 80-360 U/kg/wk or greater, rolling 3-month average Hb level of 11.0 g/dL or less (110 g/L), ferritin level greater than 500 ng/Ml, transferrin saturation (TSAT) of 20% or less and administered maintenance intravenous iron (25-100 mg/week)
- •Exclusion criteria: bone marrow malignancy, myelodysplastic syndrome, evidence of chronic infection, hemochromatosis, hemoglobinopathies, evidence of significant bleeding (decrease in Hb level = 2 g/dL during the past 3 months, mean corpuscular volume greater than 100 fL, biointact parathyroid hormone (bio-PTH) level greater than 500 pg/mL (ng/L)
Exclusion Criteria
- Not provided
Investigators
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