Comparison of 10 percent Lidocaine Spray versus 2.5 percent Lidocaine and 2.5 percent Prilocaine i.e.EMLA Cream for Attenuating Pain from Peripheral Venous Cannulation in Children: A Prospective Randomised Controlled Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 126
- Locations
- 1
- Primary Endpoint
- Pain during intravenous cannulation . Visual analogue scale score measured at the time of cannulation
Study Overview
Brief Summary
This study compares 10 percent lidocaine spray with EMLA cream made of 2.5 percent lidocaine and 2.5 percent prilocaine for reducing pain during intravenous cannulation in children aged 5 to 14 years undergoing elective surgeries. A total of 126 children will be randomly divided into two equal groups. One group will receive lidocaine spray and the other will receive EMLA cream before cannulation. The primary outcome is pain score measured using the visual analogue scale during cannulation. Secondary outcomes include heart rate changes before during and after cannulation, ease of cannulation, and local site reactions such as redness swelling and hardening at 20, 40 and 60 minutes after cannulation. The purpose of the study is to find out which topical anesthetic provides faster onset, better safety and more effective pain relief for children undergoing intravenous cannulation.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Investigator Blinded
Eligibility Criteria
- Ages
- 5.00 Year(s) to 14.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Children between 5 and 14 years undergoing elective procedures requiring anaesthesia American society of Anaesthesiologists (ASA) grade 1 and 2.
Exclusion Criteria
- •Children with difficult IV cannulation Emergency surgeries with burns, broken or infected skin Intellectual disabilities BMI above 85th percentile.
Outcomes
Primary Outcomes
Pain during intravenous cannulation . Visual analogue scale score measured at the time of cannulation
Time Frame: Pain score at the time of baseline - during the time of intravenous cannulation | and hemodynamic parameters measured five minutes before ,at the time of cannulation and five minutes after cannulation
Hemodynamic parameters like heart rate and oxygen saturation is measured
Time Frame: Pain score at the time of baseline - during the time of intravenous cannulation | and hemodynamic parameters measured five minutes before ,at the time of cannulation and five minutes after cannulation
Secondary Outcomes
- Heart rate changes before, during, after), ease of cannulation, and local side effects(Twenty , forty and sixty minutes after the cannulation)
Investigators
Shenaz Banu
Sri Venkateshwaraa Medical College Hospital and Research Centre