Comparison between the roles of low dose aspirin and folic acid in preventing preeclampsia among high risk women screened by uterine artery Doppler at

Not Applicable

• Conditions: Pregnancy and Childbirth; Preeclampsia

• Registration Number: PACTR201503001054393
• Lead Sponsor: Cairo University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-03-04
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Other
• Sex: Female
• Target Recruitment: 210

Inclusion Criteria

Uterine artery Doppler resistance index exceeds 0.68 with or without an early diastolic notch at 22-24 weeks of geatation.

-High risk patients for developing preeclampsia defined by having any of the following risk factors: chronic hypertension, pregestational diabetes mellitus, body mass index (BMI) > 30kg/m² or past history of preeclampsia

Exclusion Criteria

Multifetal pregnancy.
Antiphospholipid syndrome.
Ruptured membranes.
Major congenital anomalies.
Patients already receiving prophylactic therapy.
Patients with known allergy to aspirin or folic acid

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Preeclampsia development

Secondary Outcome Measures

Name	Time	Method
Early onset eclampsia;Severe preeclampsia