use of resveratrol in periodontitis and diabetes
Phase 4
Completed
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2022/05/042806
- Lead Sponsor
- katamneni poojitha
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Patients with moderately controlled diabetes mellitus (HbA1c 6-7)
patients with generalized pocket depth of 5- 6 mm and CAL � 5mm.
Patients having atleast 20 permanent teeth.
Should not have undergone any form of dental treatment
Exclusion Criteria
1.Patients with any systemic disease other than diabetes.
2.Habit of smoking
3.Pregnancy or lactation
4.Used antibiotics /or anti- inflammatory drugs in the last 3 months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Periodontal therapy proved to be effective in reducing the inflammatory state and oxidative stress, as well as improving the glycemic control in diabetic patients. <br/ ><br> <br/ ><br> The present study is planned to observe the benefits of systemic administration of resveratrol in chronic periodontitis patients with type II diabetes before and after scaling and rootplaning. Parameters were recorded at baseline, 7 weeks postoperative. Primary outcome parameters assessed were HbA1C, Probing pocket depth (PPD) and Clinical attachment level (CAL).Timepoint: Baseline <br/ ><br>7 weeks post operative
- Secondary Outcome Measures
Name Time Method plaque index(PI), Modified sulcular bleeding index(MSBI) as secondary outcome parameters.Timepoint: Baseline <br/ ><br>7 weeks post operative