KCT0000053招募中未知
Efficacy and safety of Escitalopram in the treatment of depressive patients with acute coronary artery syndrome: A double-blind placebo-controlled trial
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 300
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 18(Year) 至 85(Year)（—）
- 性别
- All
入选标准
- •1)Aged 18~85
- •2)Diagnosed as acute CAS (unstable angina or acute myocardial infarction) and being conducted coronary angiography
- •3)Beck Depression Inventory > 10 and major or minor depressive disorder by the DSM-IV criteria
- •4)With ability to complete various questionnaires
- •5)Can understand the objective of the study and sign informed consent
排除标准
- •1)Occurrence of acute CAS while the patient was hospitalized for another reason, except for CAS
- •2)Current CAS developed less than 3 months after coronary artery bypass graft procedure
- •3)Uncontrolled hypertension (systolic BP > 180mmHg or diastolic BP > 100mmHg)
- •4)Resting heart rate < 40/min
- •5)Severe physical illnesses threatening life or interfering with the recovery from CAS
- •6)Persistent clinically significant laboratory abnormalities
- •7)Concomitant use of class I antiarrhythmic medications; reserpine, guanethidine, clonidine, or methyldopa; anticonvulsants or neuroleptics
- •8)History of neuropsychiatric illnesses such as dementia, Parkinson's disease, brain tumor, psychoses, alcoholism, and other substance dependence
- •9)Pregnancy
研究者
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