Cardiorespiratory Autonomic Reflexes During Superselective Ophthalmic Artery Chemotherapy for Retinoblastoma in Children: a Prospective Observational Study.
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Cardiorespiratory autonomic reflexes incidence
研究概览
简要总结
Prospective observational study in patients undergoing intra-arterial ophthalmic artery chemotherapy for the treatment of retinoblastoma. The main objective of the study is to evaluate the incidence of cardiorespiratory autonomic reflexes in these patients and to investigate the association between autonomic reflexes and perioperative clinical characteristics.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients diagnosed with retinoblastoma and submitted to intra-arterial chemotherapy during the study period
- •Informed consent form signed and dated by legal guardian and investigator
- •Informed assent form signed by the patient if appropriate
排除标准
- •Refusal of the patient or guardian to participate in the research project
结局指标
主要结局
Cardiorespiratory autonomic reflexes incidence
时间窗: from the admission of the patient in the operating room until the end of the procedure (intra-arterial chemotherapy)
To evaluate the incidence of cardiorespiratory autonomic reflexes during intra-arterial chemotherapy of the ophthalmic artery in a child cancer center.
次要结局
- Clinical background and autonomic reflexes occurence(from the admission of the patient in the operating room until the end of the procedure.)
研究者
Mariana Fontes Lima Neville
Principal Investigator
Federal University of São Paulo