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Facts and Attitudes About Clinical Trials

Not Applicable
Completed
Conditions
Neoplasm
Cancer
Interventions
Behavioral: Clinical Trial educational materials
Registration Number
NCT01269645
Lead Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Brief Summary

The primary objective of this project is to examine the impact of providing cancer patients with audiovisual information about clinical trials on attitudes towards clinical trial participation. It is hypothesized that patients provided these materials will have more favorable attitudes toward clinical trial participation compared to patients not provided these materials.

Participants will be randomized to either: (1) an intervention condition in which they will be asked to view a short video and read an accompanying brochure about clinical trials developed by the investigative team; or (2) a control condition in which they will be asked to read the National Cancer Institute's brochure entitled "Taking Part in Cancer Treatment Research Studies." Self-report data will be collected at two timepoints: 1) in person following study enrollment, but before receipt of material related to intervention assignment (baseline/Time 1), and 2) by telephone interview between 7 and 28 days following study enrollment (follow-up/Time 2). In addition, data will also be collected from medical records six weeks after study enrollment.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
471
Inclusion Criteria
  1. Be diagnosed with cancer
  2. Have not been asked previously to participate in a clinical trial of a treatment for cancer
  3. Be scheduled for a visit with a medical oncologist at the time of recruitment
Exclusion Criteria
  1. Are under the age of 18
  2. Do not speak and read standard English
  3. Are unable to provide informed consent

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Clinical Trial educational materialsClinical Trial educational materialsUsual care and (1) a 10-minute clinical trials educational video; and (2) a 12-page educational booklet to accompany the educational video. Content includes basic information about clinical trials and patient testimonials about the value and benefits of participating in clinical trials. The video also addresses common misperceptions about clinical trials using patient and physician testimonials. After watching the video, participants will be provided a copy of the video for home viewing, along with the educational booklet to be reviewed at home.
Usual careClinical Trial educational materialsUsual care and provision of National Cancer Institute brochure "Taking Part in Cancer Treatment Research Studies." Participants will be asked to read this brochure after completion of the baseline surveys and will be given a copy to take home with them.
Primary Outcome Measures
NameTimeMethod
Change from baseline to follow-up in attitudes towards clinical trial participationBaseline (before first med onc visit; after first med onc visit; or before second med onc visit) and Follow-up (7-28 days after baseline)

The primary objective of this project is to examine the impact of providing cancer patients with audiovisual information about clinical trials on attitudes towards clinical trial participation. It is hypothesized that patients provided these materials will have more favorable attitudes toward clinical trial participation compared to patients not provided these materials.

Secondary Outcome Measures
NameTimeMethod
Impact of information on knowledge, self-efficacy, receptivity, and likelihood of participatingBaseline (before first med onc visit; after first med onc visit; or before second med onc visit) and Follow-up (7-28 days after baseline)

The secondary objectives are to examine the impact of audiovisual information about clinical trials on knowledge, self-efficacy, receptivity, and likelihood of participating in a clinical trial. It is hypothesized that patients provided audiovisual materials will be more knowledgeable about clinical trials, will believe themselves to be more capable of participating in a clinical trial, will be more receptive to learning more about a clinical trial, and will report greater likelihood of participating in a clinical trial if asked compared to patients not provided these materials.

Impact of information on participation in clinical trialsMedical record review (6 weeks after completion of baseline survey)

The tertiary objective is to explore the impact of providing cancer patients with audiovisual information about clinical trials on actual participation in clinical trials. Since this aim is exploratory, no hypothesis is offered.

Trial Locations

Locations (7)

Hartford Hospital

🇺🇸

Hartford, Connecticut, United States

University of Florida, Gainesville

🇺🇸

Gainesville, Florida, United States

Ocala Oncology Center

🇺🇸

Ocala, Florida, United States

H. Lee Moffitt Cancer Center & Research Institute

🇺🇸

Tampa, Florida, United States

Center for Cancer Care & Research/Watson

🇺🇸

Lakeland, Florida, United States

Space Coast Medical Associates

🇺🇸

Titusville, Florida, United States

Billings Clinic

🇺🇸

Billings, Montana, United States

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