Energy needs in adult critically ill patients with infection.

Not Applicable

Completed

• Conditions: Critical illness; Diet and Nutrition - Other diet and nutrition disorders; Public Health - Health service research

• Registration Number: ACTRN12623000906651
• Lead Sponsor: Bianca Mammana

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2023-03-13
• Study Start: 2023-08-23
• Last Update Posted: 30 October 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

Critically ill adult mechanically ventilated patients admitted to the SCGH ICU, Perth, Australia from August 2021.

- Intubated and ventilated with an expected ICU LOS greater than 24 hours
- Have a suspected infection requiring vasopressors as documented by the medical team
- Greater than or equal to 18 years of age

Exclusion Criteria

- Continuous renal replacement therapy (CRRT)
- Extracorporeal membrane oxygenation (ECMO)
- Leaking endotracheal or tracheostomy tubes
- Presence of chest drains or bronchopleural fistula
- Fraction of inspired oxygen (FiO2) greater than 50%
- Positive end-expiratory pressure (PEEP) greater than 10

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Daily energy expenditure is being measured using indirect calorimetry (QUARK RMR).[ Daily throughout ICU admission until extubation or after four weeks, whichever comes first.];Daily energy expenditure is being estimated using predictive methods (weight based, penn state and schofield equations)[ Daily throughout ICU admission until extubation or after four weeks, whichever comes first. ];Feasibility of indirect calorimetry (QUARK RMR) is being assessed by measuring time involved (using a stopwatch timer), and recording the number of tests not completed, number of tests interrupted, and reasons for test interruptions. [ Daily for each indirect calorimetry measurement until extubation or after four weeks, whichever comes first.]