Role of elastography (imaging on ultrasound) in breast cancer patients recieving chemotherapy to predict responders and non responders.chemotherapy before surgery in breast cancer patients.
Phase 2
- Conditions
- Health Condition 1: C50- Malignant neoplasm of breast
- Registration Number
- CTRI/2024/03/063796
- Lead Sponsor
- Tata Memorial Hospital, Parel
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. HPR proven Operable breast cancer patients, planned for treatment (NACT + Surgery) in TMH
2. Age more than 18 years
3. Oligometastatic disease where treatment intent is curative
Exclusion Criteria
1. Metastatic disease
2. Cystic lesion– elastography is not useful
3. DCIS with no measurable mass on USG
4. Inflammatory breast cancer
5. Pregnancy
6. Patients whose pre chemotherapy images are incomplete
7. Treatment defaulters (Patients who refuse, delay or discontinue treatment at any
time point during the study) and those who receive any treatment outside TMH.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess role of shear wave elastography in predicting the responders vs non <br/ ><br>responders to NACT in breast cancer patients.Timepoint: 2 years
- Secondary Outcome Measures
Name Time Method Subset analysis of different types and grades of breast cancers for response to NACT.Timepoint: 2 years;To predict pathological complete response in responders using elastography values. <br/ ><br>Timepoint: 2 years