To compare bupivacaine and ropivacaine in for post-operative pain relief after Elective Abdominal Hysterectomy.
Not Applicable
- Conditions
- Health Condition 1: N92- Excessive, frequent and irregularmenstruationHealth Condition 2: D25- Leiomyoma of uterusHealth Condition 3: O- Medical and SurgicalHealth Condition 4: N93- Other abnormal uterine and vaginalbleeding
- Registration Number
- CTRI/2021/12/038898
- Lead Sponsor
- Government medical collegeBhavnagar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients undergoing elective abdominal hysterectomy under subarachnoid block.
Age: 35-65 years
ASA(American society of anaesthesia) physical status I and II.
Exclusion Criteria
Contraindications to subarachnoid block like,
- Local infection or sepsis at the
site of Lumbar puncture
- Bleeding disorders,
thrombocytopenia
- Space occupying lesions of the
brain
- Anatomical disorders of the spine
- Hypovolaemia e.g. following
massive haemorrhage
Allergy to local anaesthetic drugs .
Pregnancy and lactation
Patient on any form of analgesics therapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method TO COMPARE EFFECTIVENESS OF BUPIVACAINE(0.5%) AND ROPIVACAINE(0.75%) FOR POST OPERATIVE ANALGESIA IN BILATERAL TRANSVERSUS ABDOMINIS PLANE BLOCKTimepoint: 24 hours
- Secondary Outcome Measures
Name Time Method TO COMPARE BETWEEN 2 GROUPS <br/ ><br>1)Frequency and duration of rescue analgesia required in first 24 hours <br/ ><br>2)Time for first rescue analgesic <br/ ><br>3)Effect on hemodynamic variables like heart Rate (HR) , Mean Arterial Pressure (MAP), Oxygen saturation(SpO2 ) <br/ ><br>4)Frequency of Side effects like bradycardia,hypotension, nausea , vomiting <br/ ><br> <br/ ><br>Timepoint: 24 hours