Innovation of Breakfast Cereals and Snacks for Control of Appetite and Post-Prandial Glycemia
- Conditions
- ObesityDiabetes
- Registration Number
- NCT02465021
- Lead Sponsor
- University of Toronto
- Brief Summary
The goal of the proposed research is to investigate the effects of novel snack products differing in macronutrient composition, fibre and sugar content on post-prandial glycemia and short-term appetite control in healthy adults.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- Healthy, non-smoking individuals aged 18-55 years with a body mass index of 20.0-29.9 kg/m2
- Smokers, individuals with diabetes or other cardiometabolic diseases, persons who suffer from gastrointestinal disorders or have had gastric surgery, or people who regularly use bulk laxatives
- Women with irregular menstruation or who use hormonal contraceptives or hormone replacement therapy
- Individuals who regularly skip breakfast, have allergies to any of the test food ingredients, or who follow a restrictive diet
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Food intake 120 minutes Food intake (kCal) is assessed 120 min after consumption of the treatments, using an ad libitum pizza lunch design. Participants are asked to eat, during a 20-min period, until feeling comfortably full
- Secondary Outcome Measures
Name Time Method Blood glucose 0 to 120 min (pre-ad libitum lunch) and 140 to 260 min (post-ad libitum lunch) after consumption of treatments Blood glucose (mmol/L) is measured using finger prick capillary blood samples
Perceived satiety 120 minutes Satiety scores (mm) are assessed using 100-mm "Motivation to Eat" visual analog scale questionnaires. A composite score of the four appetite questions, including Desire to Eat, Hunger, Fullness and Prospective Food Consumption, in the "Motivation to Eat" visual analog scale is calculated to obtain the average appetite score for statistical analysis
Blood insulin 0 to 120 min (pre-ad libitum lunch) and 140 to 260 min (post-ad libitum lunch) after consumption of treatments Blood insulin (μU/mL) is measured using finger prick capillary blood samples
Related Research Topics
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Trial Locations
- Locations (1)
Department of Nutritional Sciences, University of Toronto
🇨🇦Toronto, Ontario, Canada
Department of Nutritional Sciences, University of Toronto🇨🇦Toronto, Ontario, Canada