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Innovation of Breakfast Cereals and Snacks for Control of Appetite and Post-Prandial Glycemia

Not Applicable
Completed
Conditions
Obesity
Diabetes
Registration Number
NCT02465021
Lead Sponsor
University of Toronto
Brief Summary

The goal of the proposed research is to investigate the effects of novel snack products differing in macronutrient composition, fibre and sugar content on post-prandial glycemia and short-term appetite control in healthy adults.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Healthy, non-smoking individuals aged 18-55 years with a body mass index of 20.0-29.9 kg/m2
Exclusion Criteria
  • Smokers, individuals with diabetes or other cardiometabolic diseases, persons who suffer from gastrointestinal disorders or have had gastric surgery, or people who regularly use bulk laxatives
  • Women with irregular menstruation or who use hormonal contraceptives or hormone replacement therapy
  • Individuals who regularly skip breakfast, have allergies to any of the test food ingredients, or who follow a restrictive diet

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
Food intake120 minutes

Food intake (kCal) is assessed 120 min after consumption of the treatments, using an ad libitum pizza lunch design. Participants are asked to eat, during a 20-min period, until feeling comfortably full

Secondary Outcome Measures
NameTimeMethod
Blood glucose0 to 120 min (pre-ad libitum lunch) and 140 to 260 min (post-ad libitum lunch) after consumption of treatments

Blood glucose (mmol/L) is measured using finger prick capillary blood samples

Perceived satiety120 minutes

Satiety scores (mm) are assessed using 100-mm "Motivation to Eat" visual analog scale questionnaires. A composite score of the four appetite questions, including Desire to Eat, Hunger, Fullness and Prospective Food Consumption, in the "Motivation to Eat" visual analog scale is calculated to obtain the average appetite score for statistical analysis

Blood insulin0 to 120 min (pre-ad libitum lunch) and 140 to 260 min (post-ad libitum lunch) after consumption of treatments

Blood insulin (μU/mL) is measured using finger prick capillary blood samples

Trial Locations

Locations (1)

Department of Nutritional Sciences, University of Toronto

🇨🇦

Toronto, Ontario, Canada

Department of Nutritional Sciences, University of Toronto
🇨🇦Toronto, Ontario, Canada

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