EUCTR2015-001562-26-GB
Active, not recruiting
Not Applicable
Preemptive paracetamol for postoperative pain: a randomised, double blind two way crossover trial - Preemptive paracetamol for postoperative pain
niversity of Nottingham0 sitesMay 27, 2015
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversity of Nottingham
- Status
- Active, not recruiting
- Last Updated
- 10 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 18\-80 years old
- •Elective non\-malignant cervical spinal surgery
- •Capacity to give informed consent
- •Ability to use PCA device and pain score scale
- •ASA I, II and III
- •General anaesthesia
- •\>50kg in weight
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1\.2 Adults (18\-64 years) yes
Exclusion Criteria
- •Allergy or sensitivity to paracetamol, proparacetamol or morphine
- •Liver disease
- •Renal disease (creatinine clearance \<30ml/min)
- •Bleeding disorder
- •Chronic alcoholism
- •Chronic malnutrition
- •Dehydration
- •G6PD deficiency
- •Hypernatraemia (Na \>150\)
- •Hypokalaemia (K \<3\.5\) and hyperchloraemia
Outcomes
Primary Outcomes
Not specified
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Unknown
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