Role of Ultrasound-Guided Transversus Abdominis Plane Block (TAP) in decreasing pain in patients with Chronic Pancreatitis: A single arm intervention study
试验速览
- 阶段
- 2/3 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- To compare the pain relief using Visual Analogue Score (VAS) among patients of Chronic pancreatitis receiving TAP block
研究概览
简要总结
Chronic abdominal pain (pain lasting for <3 months11) seen in CP, is said to be of 2 types1:
1. Visceral Abdominal Pain Syndrome (VAPS)
Abdominal Myofascial Pain Syndrome (AMPS)
Failure to identify AMPS in patients with CP may lead to frustration for both the patients and the treating surgeon culminating in poor pain control, escalating dose of opioids, mental agony, increased hospital readmission and unreasonable investigations, surgery resulting in increasing hospital expenses. Moreover, the treatment modalities mentioned for visceral pain are ineffective in patients with AMPS. Transversus abdominis plane (TAP) block  is a well-established and a safe procedure for providing post-operative analgesia in surgical patients.
To the best of our knowledge, there is only one study in the world & no studies in India that were done to study the effectiveness of TAP block in reducing pain and to distinguish between Visceral Abdominal Pain Syndrome (VAPS) & Abdominal Myofascial Pain Syndrome (AMPS) in patients with Chronic Pancreatitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients of Chronic abdominal pain due to chronic pancreatitis within 18- 75 years of age with normal amylase / lipase with no evidence of active inflammation on CT & with VAS score of more than 3.
排除标准
- •Patients with American Society of Anesthesia (ASA) levels IV and V.
- •Pregnancy
- •Patients with Bupivacaine hypersensitivity 
- •Patients requiring surgery for chronic pancreatitis.
结局指标
主要结局
To compare the pain relief using Visual Analogue Score (VAS) among patients of Chronic pancreatitis receiving TAP block
时间窗: 2 years
次要结局
- 1. To distinguish the cause of pain into VAPS or AMPS.(2. Cumulative opioid/NSAID requirement before & after the block.)
研究者
Adithya Kamath
JIPMER, Pondicherry