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Study of Endoscopic Barrett's Esophagus Diagnosis

Terminated
Conditions
GERD
Barrett's Esophagus
Registration Number
NCT00591461
Lead Sponsor
Oregon Health and Science University
Brief Summary

Barrett's esophagus (BE) is a condition that often occurs in patients who have had GERD for a long time. The researchers are interested in BE because it can sometimes become a cancer in the esophagus. The way that we currently diagnose BE is by performing an upper endoscopy and looking for a change in the color of the esophagus. This color change may represent BE. If the doctor sees this, he/she may take biopsies of this area.

Studies have shown that making the diagnosis of BE can be hard to make. One of the reasons why this may be is because doctors may interpret what they see differently during the procedure. In other words, they may see an esophagus that appears normal in color or abnormal in color.

The purpose of this study is to compare two doctors' impressions of the appearance of the esophagus during a single endoscopy procedure.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
13
Inclusion Criteria
  • History of (h/o) GERD
  • Upper GI symptoms such as acid taste in mouth, dysphagia, dyspepsia
  • Screening or surveillance exam for BE
Exclusion Criteria
  • Unable to consent
  • History of esophageal varices

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome will be the interobserver variability in the presence of columnar epithelium as well as the measured lengths.one endoscopy visit
Secondary Outcome Measures
NameTimeMethod
variables that predict endoscopic interobserver agreement and path-confirmationone endoscopy visit
frequency of pathology-confirmed BEone endoscopy visit

Trial Locations

Locations (2)

PVAMC

🇺🇸

Portland, Oregon, United States

OHSU

🇺🇸

Portland, Oregon, United States

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