Effect of menopausal hormone therapy on blood pressure in women with mild hypertensio
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0005405
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- Female
- Target Recruitment
- 120
Postmenopausal women (duration of amenorrhea: 12 months or
longer or serum follicle-stimulating hormone value: 30 mIU/mL or higher) Grade 1
hypertension: according to clinic BP measured at the arm, systolic BP of 140 to
159 mmHg or diastolic BP of 90 to 99 mmHg. Women with uncontrolled hypertension
using antihypertensive medication for at least six months Women whose BP was
controlled but who wanted to hold their BP medication were included if the BP
rebounded only to grade 1 after two weeks of washout.
Symptomatic coronary heart disease or stroke Current or
recent (within one year prior to enrollment) smoking Uncontrolled diabetes
mellitus (glycated hemoglobin > 8%) Secondary hypertension Hypertension
with serious target organ injury suspected Current or recent (within three
months before the time of the study entry) MHT use Contraindications for MHT
including acutely impaired liver function, breast cancer, and venous
thrombosis.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ambulatory blood pressure
- Secondary Outcome Measures
Name Time Method Arterial stiffness