A study of hypoallergenic bottle feeding for infants with suspected cow's milk allergy
- Conditions
- on-IgE mediated cow's milk allergyNiet-Ige gemedieerde koemelkallergie
- Registration Number
- NL-OMON20308
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 168
Inclusion Criteria
Infants ≤12 months of age.
- Suspected non-IgE mediated CMA¡¯ as defined by a symptom score of at least 15 points and the pediatrician¡¯s opinion of a possible benefit from an elimination diet.
Exclusion Criteria
- Infants born <37 weeks gestation who require specific premature formula at time of study entry.
- Infants less than 2500 g at birth.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Time to symptom resolution<br /><br>- Grade of symptom resolution
- Secondary Outcome Measures
Name Time Method - Time point of acquired tolerance to cow's milk<br /><br>- Characteristics of children needed to switch from eHF to AAF<br /><br>- Explorative: immunology markers, microbiome analysis
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie non-IgE mediated cow's milk allergy in infants using hypoallergenic formulas?
How does hypoallergenic formula efficacy compare to standard hydrolyzed or amino acid-based formulas in non-IgE cow's milk allergy?
Which immunological biomarkers correlate with clinical response to hypoallergenic feeding in non-IgE mediated cow's milk allergy?
What adverse events are associated with hypoallergenic infant formulas in non-IgE cow's milk allergy trials and how are they managed?
Are there combination therapies or alternative feeding strategies being evaluated alongside hypoallergenic formulas for non-IgE cow's milk allergy?