Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)
- Conditions
- GliomaBrain TumorCarotid Artery StenosisIntracranial HemorrhagesIntracranial Aneurysm
- Registration Number
- NCT05968053
- Lead Sponsor
- Beijing Tiantan Hospital
- Brief Summary
Plastic particles are a ubiquitous pollutant in the living environment and food chain, so far, plenty of studies have reported the internal exposure of microplastics and nanoplastics in human tissues and enclosed body fluids.
Neurosurgery is the only department that can open the skull. In addition to blood and cerebrospinal fluid, there are brain tissue and tumors in the presence of lesions. Whether any of these microplastics and nanoplastics are present remains a mystery. This prospective observational study will harvest biological samples of neurosurgery patients.
The objective of this research is to be able to detect microplastics and nanoplastics on blood and operation samples of neurosurgery patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 500
- Age 18-80 years
- Any type of neurosurgery
·refusal of the patient to participate
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method microplastics baseline, intraoperative Detection of microplastics in human brain tissue and the blood undergoing neurosurgery
nanoplastics baseline, intraoperative Detection of nanoplastics in human brain tissue and the blood undergoing neurosurgery
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Beijing Tiantan Hospital, Capital Medical University
🇨🇳Beijing, Beijing, China