Association Between Hair Cortisol and Symptoms in Children With Psychopathology During CBT
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 主要终点
- Hair Cortisol Concentration
研究概览
简要总结
This study aims to examine the relationship between hair cortisol concentration and behavior and sleep disturbance symptoms in children with psychiatric disorders. It also investigates potential changes in hair cortisol and symptomatology after group-based cognitive behavior therapy. Furthermore, the study explores the effects of any alterations in hair cortisol concentration levels on potential behavior and sleep disturbance symptom change over the course of the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 13 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •symptoms of anxiety or depression
- •deficiencies in emotional and behavioral skills impairing functioning
- •sufficient social and cognitive skills to participate in group work.
排除标准
- •excessive physical aggression
- •excessive physical restlessness
- •severity of psychiatric symptoms requiring individual psychotherapy (e.g., acute suicidality).
结局指标
主要结局
Hair Cortisol Concentration
时间窗: Before and after the group cognitive behavioral intervention (duration from pre-GCBT to post-GCBT circa 4.7 months), and at a 7-month follow-up
Level of hair cortisol concentration measured from hair samples
Parent-rated sleep disturbance symptoms
时间窗: Before and after the group cognitive behavioral intervention (duration from pre-GCBT to post-GCBT circa 4.7 months), and at a 7-month follow-up
Sleep Disturbance Scale for Children (SDSC). A cutoff score of 39 and above has been suggested to identify children with sleep disturbance.
Parent- and teacher rated internalizing and externalizing symptoms
时间窗: Before and after the group cognitive behavioral intervention (duration from pre-GCBT to post-GCBT circa 4.7 months), and at a 7-month follow-up
The Achenbach System of Empirically Based Assessment (ASEBA). Scores below 60 reflect the normal range, scores from 60 to 63 the borderline range, and scores above 63 the clinical range
Child-rated internalizing symptoms
时间窗: Before and after the group cognitive behavioral intervention (duration from pre-GCBT to post-GCBT circa 4.7 months), and at a 7-month follow-up
The Spence Children´s Anxiety Scale. A total score of 60 or higher is indicative of elevated anxiety.
次要结局
未报告次要终点
研究者
Sarianna Barron-Linnankoski
Principal Investigator
Helsinki University Central Hospital