sing molecules in saliva to detect cancer of the mouth
Not Applicable
- Conditions
- Health Condition 1: C01- Malignant neoplasm of base of tongueHealth Condition 2: C04- Malignant neoplasm of floor of mouthHealth Condition 3: C03- Malignant neoplasm of gumHealth Condition 4: C050- Malignant neoplasm of hard palateHealth Condition 5: C06- Malignant neoplasm of other and unspecified parts of mouth
- Registration Number
- CTRI/2019/11/022070
- Lead Sponsor
- Tata Centre for Development at the University of Chicago
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Case: Patients diagnosed of Oral Squamous Cell carcinoma, yet to undergo any therapeutic intervention
Exclusion Criteria
Patients diagnosed with any other disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Create a biomarker gene panel, based on previous work done in India and US, that contains the most commonly occurring mutations in OCSCC. <br/ ><br>Evaluate the diagnostic and prognostic accuracy of released tumor DNA (rtDNA) in saliva in patients with early stage OCSCC <br/ ><br>Timepoint: After about 6 months (April 2020)
- Secondary Outcome Measures
Name Time Method To use rtDNA to detect genetic mutation that will enable early detection of oral cancerTimepoint: One year