Retrospective Analysis of Intraoperative Volume Administration in Neonates Without Congenital Malformations With Very Low Birth Weight and Acute Abdomen.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 89
- 试验地点
- 1
- 主要终点
- Postoperative Capillary Leakage
研究概览
简要总结
Objective:
Due to high mortality rates the capillary leakage and the acute abdomen are important risk factors of the probability of survival. The aim of an optimal therapy of the acute abdomen within the neonatal period is beside the cure of the underlying disease the prophylaxis of capillary leakage with the help of optimised intra- and postoperative volume therapy.
Question:
Do the neonates with very low birth weight and a surgery therapy of acute abdomen benefit from early increase of the haemoglobin/haematocrit by optimised volume therapy with crystalloid and colloidal volume as prophylaxis of the capillary leakage?
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Minute 至 4 Weeks（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Postoperative Capillary Leakage
时间窗: 48 hours from Baseline (Operation)
Postoperative Capillary Leakage (defined as weight gain within 48 hours or development of oedema within 48 hours)
次要结局
- Amount of transfusions during surgery(Up to 5 hours)
- Re-surgery rate(Participants will be followed for the duration of hospital stay, an expected average of 12 weeks)
- Length of stay(Participants will be followed for the duration of hospital stay, an expected average of 12 weeks)
- Mortality(Up to 1 year)
研究者
Claudia Spies
Department of Anesthesiology and Intensive Care Medicine, CVK and CCM
Charite University, Berlin, Germany