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Neonates With Very Low Birth Weight and Surgery Therapy of Acute Abdomen

Completed
Conditions
Very Low Birth Weight
Registration Number
NCT01817062
Lead Sponsor
Charite University, Berlin, Germany
Brief Summary

Objective:

Due to high mortality rates the capillary leakage and the acute abdomen are important risk factors of the probability of survival. The aim of an optimal therapy of the acute abdomen within the neonatal period is beside the cure of the underlying disease the prophylaxis of capillary leakage with the help of optimised intra- and postoperative volume therapy.

Question:

Do the neonates with very low birth weight and a surgery therapy of acute abdomen benefit from early increase of the haemoglobin/haematocrit by optimised volume therapy with crystalloid and colloidal volume as prophylaxis of the capillary leakage?

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
89
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Postoperative Capillary Leakage48 hours from Baseline (Operation)

Postoperative Capillary Leakage (defined as weight gain within 48 hours or development of oedema within 48 hours)

Secondary Outcome Measures
NameTimeMethod
Amount of transfusions during surgeryUp to 5 hours
Re-surgery rateParticipants will be followed for the duration of hospital stay, an expected average of 12 weeks
Length of stayParticipants will be followed for the duration of hospital stay, an expected average of 12 weeks
MortalityUp to 1 year

Trial Locations

Locations (1)

Department of Anesthesiology and Intensive Care Medicine, CCM and CVK, Charité - University Berlin

🇩🇪

Berlin, Germany

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