Three Different Laparoscopic Approaches for Ovarian Endometrioma and the Effect on Ovarian Reserve

Not Applicable

• Conditions: Endometriosis
• Interventions: Procedure: laparoscopic ovarian endometriotic cyst

• Registration Number: NCT02754648
• Lead Sponsor: Ain Shams University

Brief Summary

Is ovarian reserve and fecundity rate higher with laparoscopic ovarian aspiration rather than laparoscopic ovarian cystectomy and laparoscopic ovarian de-roofing in infertile woman with ovarian endometrioma or not?

Detailed Description

Primary objective:

To assess antral follicular count before and after treatment of endometriotic cyst either by aspiration, stripping, de-roofing and bed cauterization.

Secondary objectives To assess anti mullerian hormone level, follicle stimulating hormone level ,Doppler blood flow before and after treatment of endometriotic cyst either by aspiration, stripping, de-roofing and bed cauterization.

Study Timeline

• Study Start: 2015-09
• Study First Submitted: 2016-03-16
• Status Verified: 2016-04
• Study First Submitted QC: 2016-04-26
• Last Update Submitted: 2016-04-26
• Study First Posted: 2016-04-28
• Last Update Posted: 2016-04-28
• Primary Completion: 2016-09
• Study Completion: 2016-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

• Infertile woman aged 18-35 years old.
• Endometriotic ovarian cyst with size less than or equal 5 cm.

Exclusion Criteria

• Other than included criteria.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
group B; laparoscopic ovarian endometrial stripping	laparoscopic ovarian endometriotic cyst	Laparoscopic ovarian endometrial stripping will be done for thirty patients with ovarian endometriotic cyst.
Group c laparoscopic ovarian endometrial de-roofing	laparoscopic ovarian endometriotic cyst	Laparoscopic ovarian endometrial de-roofing and bed cauterization will be done for thirty patients with ovarian endometriotic cyst.
Group A; laparoscopic ovarian endometrial aspiration	laparoscopic ovarian endometriotic cyst	Laparoscopic ovarian endometrial aspiration will be done for thirty patients with ovarian endometriotic cyst. .

Primary Outcome Measures

Name	Time	Method
The antral follicular count which records the number of visible ovarian follicle (2-10 mm mean diameter) seen by transvaginal ultrasound on menstrual cycle( days 2_5)	One month	Cut point(3-10)

Secondary Outcome Measures

Name	Time	Method
Anti mullerian hormone level in blood secreted by antral follicles 2-6 mm diameter in ovary	One month	Measure in ng/ml cut point is( 0.2-0.7)
Follicle stimulating hormone in blood secreted by antral follicles on day 2-4 of menstrual cycle	One month	Cut point is(10-20) measured in international unit/litre