Rheumatic Heart Disease Community Streptococcal Treatment Program "RESET"
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 66,123
- 试验地点
- 1
- 主要终点
- Determination of Echocardiography prevalence of RHD among children 5-15 years old
研究概览
简要总结
The primary objective of this study is to determine the impact of a pragmatic RHD primary prevention program in Uganda.
The secondary Objective are as follow:
- To improve guideline-based care for sore throat through frontline healthcare provider education on clinical decision rules and guideline-based primary prevention.
- To increase health seeking behavior for sore throat thorough a multifaceted community awareness campaign.
详细描述
Our intervention is designed as a service-oriented plan to be implemented through the primary healthcare structure and facilities of both the national health and private system. Additional support will come from the education system, with participation from schools, teachers, patients, patient families, and the public. Our intervention will focus on two of the more easily rectified impediments to primary prevention, namely (1) poor uptake of guideline-based treatments for Group A Streptococcal (GAS) pharyngitis and (2) low levels of public awareness of the importance of sore throat care and treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 5 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Has agreed to participate in the study via the study's informed consent/assent process.
排除标准
- •Known history of ARF or RHD
- •Any known co-morbid conditions (HIV, renal deficiencies, severe malnutrition,
- •among others) that have resulted in prescription of regular antibiotic prophylaxis
- •Structural or functional cardiac defects, other than those consistent with RHD, that were known prior to or detected through echo screening (except patent foramen ovale, small atrial septal defect, small ventricular septal defect, small patent ductus arteriosus).
结局指标
主要结局
Determination of Echocardiography prevalence of RHD among children 5-15 years old
时间窗: 2 year endpoint
Echocardiography screening of school age children in Uganda to determine prevalence of RHD prior to and 2 years post intervention
次要结局
未报告次要终点