NL-OMON30062招募中3 期
Efficacy of Inhaled RhDNase in Mechanically Ventilated Pediatric Patients with an Atelectasis - RhDNase in ventilated pediatric patients
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 2 至 17（—）
入选标准
- •1. Age 0-18 years
- •2. Mechanical ventilation
- •3. Presence of an atelectasis on a chest radiograph (CXR)
- •4. First dose of study medication can be administered within 12 hours after an atelectasis has been diagnosed.
排除标准
- •1. Children with neuromuscular disorders and impaired ability to cough; cardiomyopathy; or cystic fibrosis.
- •2. Post-gestational age < 32 weeks
- •3. Mechanical ventilation during muscle paralysis
- •4. Atelectasis due to a bronchoscopically diagnosed:
- •- foreign body aspiration
- •- tracheal or bronchial compression by lymph nodes or vessels
- •5. RhDNase treatment in the previous 48 hours.
- •6. Clinical condition or ventilator settings that are not compatible with nebulizing medication (according to the responsible physician)
- •7. Presence of a pneumothorax
研究者
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