The effectiveness of rhBMP-2 injected on palatal expansion.
Phase 1
Recruiting
- Conditions
- Cleft lip and palate patients.Cleft palate with cleft lip
- Registration Number
- IRCT2017051533974N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
cleft lip and palate patients; aged over 11 years showing after puberty stage (before CS3) based on cervical vertebral stadium (CVS).
Exclusion criteria: Having certain systemic diseases; unwillingness to continue the study
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Width between canines. Timepoint: Before, as well as immediately and 3 months after intervention. Method of measurement: Cone beam computed tomography (CBCT).;First pre-cooled. Timepoint: Before, as well as immediately and 3 months after intervention. Method of measurement: Cone beam computed tomography (CBCT).;Volume and density of alveolar bone defects. Timepoint: Before, as well as immediately and 3 months after intervention. Method of measurement: Cone beam computed tomography (CBCT).;First permanent molar. Timepoint: Before, as well as immediately and 3 months after intervention. Method of measurement: Cone beam computed tomography (CBCT).
- Secondary Outcome Measures
Name Time Method