BioDulse: The Effect of an Irish Seaweed Protein Extract on Glucose Control in Healthy Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- Postprandial blood glucose area under the curve (AUC)
研究概览
简要总结
Co-ingesting protein with carbohydrate is an effective way to improve postprandial glucose handling. The investigators have isolated and identified a bioactive protein extracted from seaweed. The investigators aim to explore how varying doses of seaweed protein influence postprandial glycaemia and insulinaemia in a healthy population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 67 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aged 18-67
排除标准
- •Terminal disease
- •Past medical history of vascular disease, cancer, diabetes, neurological, kidney, pulmonary, digestive (Coeliac disease), thyroidal disease, cognitive impairment;
- •Exclusively receiving enteral or parenteral nutrition,
- •Any conditions/anomalies that are contraindications to bioelectrical impedance analysis as per institutional risk assessment and SOP.
研究组 & 干预措施
Low protein
0.6g/kg body mass maltodextrin PLUS 0.075g/kg body mass protein from Biodulse, in solution
干预措施: Seaweed protein (Dietary Supplement)
Medium protein
0.6g/kg body mass maltodextrin PLUS 0.15g/kg body mass protein from Biodulse, in solution
干预措施: Seaweed protein (Dietary Supplement)
Control
0.6g/kg body mass maltodextrin in solution.
干预措施: Seaweed protein (Dietary Supplement)
结局指标
主要结局
Postprandial blood glucose area under the curve (AUC)
时间窗: 120 min
Integrated area under curve of blood glucose concentration (measured as mmol/L) over 120min
次要结局
- Timecourse of blood glucose concentration(0, 15, 30, 45, 60, 90, 120 min)
- Postprandial serum insulin concentration(0, 15, 30, 45, 60, 90, 120 min)
- Postprandial serum insulin area under the curve (AUC)(120 min)