Elucidation of effects of acute endurance exercise on novel peptide hormone
- Conditions
- Healthy males and females
- Registration Number
- JPRN-UMIN000021308
- Lead Sponsor
- Waseda University
- Brief Summary
Twenty-eight subjects participated in the experiment, of whom 13 were excluded mainly because of a serum FGF21 level below the limit of detection. Thus, data from seven young (age: 18-22 years) and eight elderly male subjects (age: 62-69 years) were analysed. Participants were asked to perform a cycling exercise for 30 min at 70% maximal oxygen uptake, following carbohydrate intake. Blood samples were collected pre-exercise and 0 min, 30 min, 1 h, 3 h and 24 h after the cessation of exercise. Higher serum FGF21 was observed in the elderly subjects group throughout the experiment (P < 0.05). There was no significant increase in serum FGF21 levels after the cessation of exercise, whereas serum FGF21 levels were significantly lower 24 h after the exercise compared with those pre-exercise, 0 min, 30 min and 1 h after the cessation of exercise in both groups (P < 0.01).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Not provided
Subject who could not perform exercise and/or who have chronic diseases
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effects of acute endurance exercise on circulating peptide hormone level
- Secondary Outcome Measures
Name Time Method Effects of acute endurance exercise on blood biochemical parameters