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Estimation of Galectin-1 and Runx2 in generalized periodontitis and diabetes

Not Applicable
Completed
Conditions
Health Condition 1: E119- Type 2 diabetes mellitus without complications
Registration Number
CTRI/2023/03/050958
Lead Sponsor
Bhavana Vunnam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Age group 35-75 years.

2. Patients who have not received

any periodontal treatment in previous six months.

3. Patients diagnosed with T2DM as per American Diabetes Association criteria (2019).

4. Patients with a diagnosis of generalized periodontitis as per World Workshop Classification criteria (2017).

Exclusion Criteria

1.Smokers and alcoholics.

2.Patients with systemic diseases like hypertension, cardiovascular diseases, rheumatoid arthritis, tumours, autoimmune diseases and renal diseases.

3.Pregnant, lactating females and post menopausal women.

4.Any other systemic disease which can alter the course of periodontal disease.

5.Patients on medications like anti-inflammatory drugs, antibiotics and anti-epileptic drugs in the past 6 months.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
comparatively evaluate salivary and serum levels <br/ ><br>of Galectin-1 and Runx2 in generalized periodontitis and T2DM. <br/ ><br>Explore any correlation of Galectin-1 with Runx2 levels and clinical parameters <br/ ><br>Timepoint: Baseline
Secondary Outcome Measures
NameTimeMethod
not applicableTimepoint: not applicable
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