Comparison of Sequential therapy for eradication of H. Pylori infection in renal failure patients
- Conditions
- Helicobacter pylori infection.Helicobacter pylori
- Registration Number
- IRCT201201231241N3
- Lead Sponsor
- Department of Research and Technology, Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
patients with dyspepsia symptoms over the past one month from gastroenterology or nephrology clinic or hospital dialysis ward who have infection with H. Pylori confirmed by rapid urease test and biopsy in endoscopy. Exclusion Criteria : taking antibiotic regimen to eradicate H. pyloriand or receiving proton pump inhibitors, Bismuth, or NSAID during the last month; concomitant anticoagulant, corticosteroid or Ketoconazole; history of gastric or esophageal surgery; sensitivity to antibiotics; negative endoscopic biopsy; drinking alcohol and smoking; pregnancy and lactation; severe heart disease; diseases of the thyroid gland or liver cancer; chronic renal failure patients who are prior to stage 5 or have not received renal replacement therapy.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Eradication of Helicobacter pylori Infection. Timepoint: At the end of four weeks after treatment. Method of measurement: Urea Test.;Eradication of Helicobacter pylori Infection. Timepoint: At the end of four weeks after treatment. Method of measurement: Creatinine Clearance Test.;Eradication of Helicobacter pylori Infection. Timepoint: At the end of four weeks after treatment. Method of measurement: Stool examination.;Eradication of Helicobacter pylori Infection. Timepoint: At the end of four weeks after treatment. Method of measurement: Biopsy by Endoscopic.
- Secondary Outcome Measures
Name Time Method Acute Renal Failure. Timepoint: At the first and second weeks of treatment. Method of measurement: Testing Urea.;Acute Renal Failure. Timepoint: At the first and second weeks of Treatment. Method of measurement: creatinine clearance test.;Acute Renal Failure. Timepoint: at the first and second weeks of treatment. Method of measurement: weight.