Speech Flexibility in Adulthood Following Oral Cancer Treatment: Acoustic and Kinematic Explorations
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Articulatory gestures
研究概览
简要总结
The goal of this longitudinal study is to learn more about the articulatory consequences of surgical oral cancer treatment. The main aims are to study the coordination and development of speech articulation of patients who will undergo surgical treatment for oral cancer longitudinally and whether individual differences in the reliance on auditory or tactile information can predict the success of speech compensatory strategies.
Participants will perform multiple speech tasks while motion tracking sensors track the articulatory gestures.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Diagnosed with T1 or T2 tumor in the oral cavity
- •At least 18 years old and able to provide informed consent
- •Native speaker of Dutch
- •Has nog been treated for oral cancer before
排除标准
- •1a. Recurrence of disease (for patients)
- •1b. Treated for oral cancer (for healthy controls)
- •Speech problems (e.g., stuttering)
- •Problems with sight or hearing that impede reading or understanding instructions. When glasses or a hearing aid resolve these problems, then participants are not excluded.
- •Neurological or psychological disorders (e.g., stroke)
- •Non-removable metal in, on or around the head (piercings, braces, pacemaker, electrodes)
- •Self-reported signs of depression
结局指标
主要结局
Articulatory gestures
时间窗: 2022-2025
Articulatory movements in three dimensions of the tongue, lips and jaw as measured by the NDI Vox Electromagnetic Articulograph. Measures include: articulator speed (mm/s), total displacement (mm), coordinates (x,y,z) during specific gestures.
Acoustic outcomes
时间窗: 2022-2025
Speech acoustics will be measured in Praat and include the first and second formants of vowels (in Hz), global movement size in terms of acoustic working space (Hz-squared), and the centre of gravity of sibilants (in Hz)
次要结局
未报告次要终点