The Effect of Menstrual Cycle Phase on Muscle Protein Synthesis Following Protein Ingestion and Resistance Exercise in Young Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Muscle protein synthesis
研究概览
简要总结
The combination of dietary protein ingestion and resistance exercise are essential to increase muscle protein synthesis. The vast majority of studies assessing protein intake following resistance exercise in young adults has been conducted exclusively in men or in studies where both men and women are assessed. The increase in muscle mass is thought to be impacted by sex hormones that fluctuate across different phases of the menstrual cycle. However, the effect of menstrual cycle phase on muscle protein synthesis following exercise is not known.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female, aged 18-40 years
- •BMI between 18 and 30 kg/m2
- •Recreationally active
- •Regular menstrual cycle
排除标准
- •Smoking or use of tobacco containing products
- •Irregular menstrual cycle
- •Currently on any form of hormonal contraception
- •Post-menopausal
- •Pregnant or breastfeeding
- •Diagnosed metabolic/pulmonary/musculoskeletal illness
- •Diagnosed cardiovascular disease or hypertension
- •Use of medications that may impact protein metabolism or are anti-inflammatory
- •Gastrointestinal disorders
- •Allergy to pomegranate or amino acids
- •Injuries that would impact ability to complete study
研究组 & 干预措施
Follicular
Follicular phase assessment of muscle protein synthesis.
干预措施: Phase of the menstrual cycle (Other)
Luteal
Luteal phase assessment of muscle protein synthesis
干预措施: Phase of the menstrual cycle (Other)
结局指标
主要结局
Muscle protein synthesis
时间窗: 7 hours
The rate of synthesis of new muscle protein
次要结局
- Plasma amino acid kinetics(7 hours)
- Sex hormone concentrations(5 minutes)
- Serum insulin concentrations(7 hours)
- Energy expenditure(20 minutes)