NCT05609162Enrolling By Invitation不适用
Effects of Local and Systemic Treatments in Brain Metastases With Poor Prognostic Factors: Multicenter Retrospective Study
Sun Yat-sen University1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2022年12月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- OS
研究概览
简要总结
The goal of this observational study is to learn about treatments in brain metastases with poor prognostic factors. The main questions it aims to answer are:
- What kind of local treatment provides a survival benefit for patients with poor prognostic factors?
- What kind of systemic treatment provides a survival benefit for patients with poor prognostic factors?
- Will the combination of local treatment and systemic treatment provide a survival benefit for patients with poor prognostic factors?
Participants will be asked to provide personal information about their living status, symptoms, and disease control during the follow-up.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Evidence of pathological diagnosis of primary tumor;
- •Brain metastases confirmed by enhanced magnetic resonance imaging;
- •Complete clinical information
排除标准
- •Survival time less than 30 days;
- •If surgical treatment is accepted, the surgical treatment is not tumor resection, but ventricle puncture, biopsy and other non-tumor reducing surgery;
- •Incomplete clinical data;
- •Patients with 2 or more types of tumors.
结局指标
主要结局
OS
时间窗: From date of first follow-up until the date of documented death from any cause, assessed up to 120 months
Overall survival time
次要结局
- PFS(From date of first follow-up until the date of first documented progression, assessed up to 120 months)
研究者
Yonggao Mou
Department of Neurosurgery
Sun Yat-sen University
研究点 (1)
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