Effect of Remote Ischemic Preconditioning on Acute Kidney Injury in Patients Undergoing Heart Valve Replacement Surgery With Cardiopulmonary Bypass
Not Applicable
Completed
- Conditions
- Heart Valve Disease
- Interventions
- Procedure: Automated cuff-inflator
- Registration Number
- NCT01023152
- Lead Sponsor
- Yonsei University
- Brief Summary
The purpose of this study is to study the effect of remote ischemic preconditioning on acute kidney injury in patients undergoing heart valve replacement surgery with cardiopulmonary bypass.
- Detailed Description
Hypothesis : RIPC using tourniquet might be a simple technique with the benefit to provide renal protection without disturbing operating procedure and prolongation of total operating time.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
- patients undergoing complex valve surgery.
Exclusion Criteria
- older than 80 years
- those with left main disease >50%, or hepatic or pulmonary disease
- active infective endocarditis
- left ventricular ejection fraction <30%
- myocardial infarction (MI) within 3 weeks
- pre-existing renal dysfunction (serum creatinine (Cr) level >1.4 mg/dl), and those with peripheral vascular disease affecting the lower limbs.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Automated cuff-inflator Automated cuff-inflator -
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method