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Clinical Trials/NCT05369299
NCT05369299
Completed
Not Applicable

Clinical Outcome of Two-piece Zirconia Implants in Immediate Implant Placement - a Prospective Randomized Controlled Clinical Trial

Medical University of Graz1 site in 1 country33 target enrollmentMay 13, 2022

Overview

Phase
Not Applicable
Intervention
Implant Straumann® Pure Ceramic Two Piece Implant
Conditions
Immediate Implantation of Two-piece Zirconia Dental Implants
Sponsor
Medical University of Graz
Enrollment
33
Locations
1
Primary Endpoint
Change of ISQ
Status
Completed
Last Updated
3 months ago

Overview

Brief Summary

The purpose of the study is to test whether a two-piece zirconia implant is as reliable in the indication of immediate implant placement as a standard titanium implant.

Registry
clinicaltrials.gov
Start Date
May 13, 2022
End Date
December 12, 2025
Last Updated
3 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Medical University of Graz
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients giving informed consent to participate in the clinical trial and fulfil the following criteria will be included in the investigation:
  • good oral hygiene standard;
  • good general health;
  • 18 years or older;
  • non-smokers;
  • presence of single-tooth or multiple gaps in the mandible or the maxilla;
  • intact facial bone wall;
  • sufficient bone volume to support an implant of at least 10 mm length.
  • Teeth with removable periapical lesions are included.

Exclusion Criteria

  • Primary exclusion criteria are as follows:
  • parafunctional habits;
  • active periodontitis;
  • acute or chronic medical conditions for which implant therapy has always been considered a contraindication: uncontrolled diabetes (HbA1c \>8.0%), mucosal disease, untreated periodontitis, immunological disorders, active malignancy, alcoholism, condition after radiation therapy to the head and neck area and antiresorptive therapy.
  • Secondary exclusion criteria will be applied at surgical procedure:
  • loss of facial bone wall due to extraction procedure;
  • insufficient primary stability (less than 32Ncm insertion torque).

Arms & Interventions

Two-piece zirconia implants

Immediate dental implant placement will be performed by using the new two-piece zirconia implant Straumann® Pure Ceramic Two Piece Implant

Intervention: Implant Straumann® Pure Ceramic Two Piece Implant

Two-piece titanium implants

Immediate dental implant placement will be performed by using the conventional two-piece titanium implant Neoss® ProActive Tapered Implant

Intervention: two-piece titanium implant Neoss® ProActive Tapered Implant

Outcomes

Primary Outcomes

Change of ISQ

Time Frame: initial, 6 and 12 months after surgical procedure

Implant stability quotient. A transducer (smart-peg sensor) will be installed on the top of the implant to measure ISQ with resonance frequency analysis. ISQ will be measured from 4 different sites (facial, lingual, mesial, distal) and calculated as mean of measurements.

Change of PTV

Time Frame: initial, 6 and 12 months after surgical procedure

Periotest value, Damping capacity assessment. For Periotest values, a customizable healing abutment will be inserted to assess damping capacity.

Secondary Outcomes

  • Change of BOP(initial, 6 and 12 months after surgical procedure)
  • Mean insertion time(at time of surgery)
  • Complications - esthetic(12 months after surgical procedure)
  • Change of marginal bone loss(6 and 12 months after surgical procedure)
  • Change of PES(6 and 12 months after surgical procedure)
  • Complications - biological(12 months)
  • Complications - technical(12 months after surgical procedure)
  • Change of PROM(initial, 12 months after surgical procedure)
  • Change of width of keratinized mucosa(initial, 12 months after surgical procedure)
  • Gingival biotype(initial)
  • Complications - biological(at time of surgical procedure, 2 weeks, 6 months and 12 months after surgical procedure)
  • Complications - biological(at time of surgical procedure)
  • Complications - biological(2 weeks)
  • Complications - biological(6 months)
  • Complications - technical(at time of surgical procedure)
  • Complications - technical(2 weeks)
  • Complications - technical(6 months)
  • Complications - esthetic(at time of surgical procedure)
  • Complications - esthetic(2 weeks)
  • Complications - esthetic(6 months)

Study Sites (1)

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