Determination of the local inflammatory response in patients with COPD by wood smoke and COPD per cigarette

Not Applicable

Recruiting

• Conditions: Chronic Obstructive Pulmonary Disease (COPD); Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive, Lung Diseases, Respiratory Tract Diseases

• Registration Number: RPCEC00000210
• Lead Sponsor: Fundacion Neumologica Colombiana (FNC)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-02-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

1. Patients with COPD defined by spirometric criteria diagnostic of GOLD
2. Exposure to smoke by cigarrette with package / year indice greater than 10 P / A
3. Exposure to wood smoke for over 10 years
4. Age older than 40 and younger than 90 years
5. Acceptance of the informed consent

Exclusion Criteria

1. Medical history of lung diseases such as history of asthma, cystic fibrosis, tuberculosis, bronchiectasis
2. Presence of lower respiratory tract infection in the four weeks prior to sampling.
3. History of exacerbation of the disease in the four weeks prior to sampling.
4. Patients with severe COPD according to GOLD classification
5. Immunosuppression by comorbidities (autoimmune disease, cancer, chronic use of corticosteroids, HIV infection).
6. Simultaneous exposure to wood smoke and smoking.
7. Inability to perform spirometry
8. Inability sampling induced sputum
9. No acceptance of the informed consent

Study & Design

• Study Type: Observational
• Study Design: Not specified